@floating Have you had any luck looking at this?
I'm trying to connect Frame to a Ledger Nano S on a Macbook Air. I'm using Ledger V1.5.5 and Frame V0.1.2. I cannot connect ("No Signer Connected") but if I restart Frame after I've connected the Ledger device I can get Frame to connect ("Select the Ethereum application on you Ledger") but when I select the Ethereum app on the Ledger then Frame displays "Removing" and I'm back where I started. I can connect to the Ledger device using LedgerLive fine and i can move funds to the Eth wallet on the device OK too. What am I doing wrong?
NB This is on Mainnet and MacOS 10.14.4.