thanks @iangilman , I would like to know, is possible to load 8000 resolution image as the background image, on top of that i need to add a png image of same resolution, above that need to place a map with highlight "similar to https://openlayers.org/en/latest/examples/vector-layer.html example"
The highlight could also be yet another OSD image. You could also use some sort of overlay. The open layers example seems to be using an SVG overlay... you can do that with OSD with https://github.com/openseadragon/svg-overlay
OSD doesn't have any built in geo support, though, so if you're wanting geo features you might be better off with open layers or leaflet.