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Inspired by one of the defects you quoted above, I dragged the window from my primary monitor to the second one and this solved the problem. This can't be the solution, however, since the problem returns if the application is re-started.
It didn't seem to be so yesterday but switching from full screen and back also solves the problem.
Changing UI/HiDPI scaling seems to have no effect.
Python 3.6.4 64bits